POTENTIATION OF SUXAMETHONIUM BY TACRINE
نویسندگان
چکیده
منابع مشابه
An appraisal of tacrine-extended suxamethonium.
The use of tacrine-extended suxamethonium in 117 cases is described. The extent of the myoneural block was monitored with the aid of a nerve stimulator. In patients in whom an intubating dose of suxamethonium unaccompanied by tacrine produced a somewhat prolonged apnoea, there was a significant but relatively unimportant prolongation of the action of tacrine-extended suxamethonium. Dual block d...
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Tacrine and suxamethonium were used to produce muscle relaxation in 29 anaesthetized patients. Relaxation was monitored with a nerve stimulator. Post-tetanic facilitation was observed in 24 patients (83 per cent). In spite of this, operating conditions were satisfactory in 26 patients. Poor operating conditions were associated with the more severe degrees of phase II block as judged by an incre...
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The pattern of relaxation of the cricopharyngeal sphincter by suxamethonium was studied in fifty patients. The pattern was variable, but a large percentage of the cases showed an abrupt initial fall in cricopharyngeal sphincteric tone concomitant with, or just preceding, the onset of fasciculations, although relaxation often only reached completion after fasciculations had ceased. Of twenty-thr...
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No drugs in anaesthesia are more problematic than suxamethonium. Yet, no drugs have survived as suxamethonium does in spite of crisis after crisis, and attempt after attempt at its replacement. For decades, suxamethonium has taught us neuromuscular pharmacology and provided us with an encyclopaedia of side effects, while benefiting millions and millions of our anaesthetised patients. With the a...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1965
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1965.tb02516.x